1              Menuchin-Lasowski, Y., Dagan, B., Conidi, A., Cohen-Gulkar, M., David, A., Ehrlich, M. et al. Zeb2 regulates the balance between retinal interneurons and muller glia by inhibition of BMP-Smad signaling. Dev Biol, (2020).

2              Lam, P. T., Padula, S. L., Hoang, T. V., Poth, J. E., Liu, L., Liang, C. et al. Considerations for the use of Cre recombinase for conditional gene deletion in the mouse lens. Human genomics 13, 10, (2019)

3              Cohen-Tayar, Y., Cohen, H., Mitiagin, Y., Abarbanel, Z., Levy, C., Idelson, M. et al. Pax6 regulation of Sox9 in the retinal pigmented epithelium controls its timely differentiation and choroid vasculature development. Development, (2018)

4              Swisa, A., Avrahami, D., Eden, N., Zhang, J., Feleke, E., Dahan, T. et al. PAX6 maintains beta cell identity by repressing genes of alternative islet cell types. J Clin Invest 127, 230-243, (2017)

5              Remez, L. A., Onishi, A., Menuchin-Lasowski, Y., Biran, A., Blackshaw, S., Wahlin, K. J. et al. Pax6 is essential for the generation of late-born retinal neurons and for inhibition of photoreceptor-fate during late stages of retinogenesis. Dev Biol, (2017)

6              Amram, B., Cohen-Tayar, Y., David, A. & Ashery-Padan, R. The retinal pigmented epithelium - from basic developmental biology research to translational approaches. Int J Dev Biol 61, 225-234, (2017)

7              Sun, J., Zhao, Y., McGreal, R., Cohen-Tayar, Y., Rockowitz, S., Wilczek, C. et al. Pax6 associates with H3K4-specific histone methyltransferases Mll1, Mll2, and Set1a and regulates H3K4 methylation at promoters and enhancers. Epigenetics Chromatin 9, 37 (2016)

8              Naftelberg, S., Abramovitch, Z., Gluska, S., Yannai, S., Joshi, Y., Donyo, M. et al. Phosphatidylserine Ameliorates Neurodegenerative Symptoms and Enhances Axonal Transport in a Mouse Model of Familial Dysautonomia. PLoS Genet 12, e1006486, (2016)

9              Menuchin-Lasowski, Y., Oren-Giladi, P., Xie, Q., Ezra-Elia, R., Ofri, R., Peled-Hajaj, S. et al. Sip1 regulates the generation of the inner nuclear layer retinal cell lineages in mammals. Development 143, 2829-2841, (2016)

10           He, S., Limi, S., McGreal, R. S., Xie, Q., Brennan, L. A., Kantorow, W. L. et al. Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation. Development 143, 1937-1947, (2016)

11           Gueta, K., David, A., Cohen, T., Menuchin-Lasowski, Y., Nobel, H., Narkis, G. et al. The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis. Development, (2016)

12           Bachmann, C., Nguyen, H., Rosenbusch, J., Pham, L., Rabe, T., Patwa, M. et al. mSWI/SNF (BAF) Complexes Are Indispensable for the Neurogenesis and Development of Embryonic Olfactory Epithelium. PLoS Genet 12, e1006274, (2016).

13           Sun, J., Rockowitz, S., Xie, Q., Ashery-Padan, R., Zheng, D. & Cvekl, A. Identification of in vivo DNA-binding mechanisms of Pax6 and reconstruction of Pax6-dependent gene regulatory networks during forebrain and lens development. Nucleic Acids Res, (2015)

14           Ohana, R., Weiman-Kelman, B., Raviv, S., Tamm, E. R., Pasmanik-Chor, M., Rinon, A. et al. MicroRNAs are essential for differentiation of the retinal pigmented epithelium and maturation of adjacent photoreceptors. Development 142, 2487-2498, (2015)

15           Carpenter, A. C., Smith, A. N., Wagner, H., Cohen-Tayar, Y., Rao, S., Wallace, V. et al. Wnt ligands from the embryonic surface ectoderm regulate 'bimetallic strip' optic cup morphogenesis in mouse. Development 142, 972-982, (2015)

16           Raviv, S., Bharti, K., Rencus-Lazar, S., Cohen-Tayar, Y., Schyr, R., Evantal, N. et al. PAX6 regulates melanogenesis in the retinal pigmented epithelium through feed-forward regulatory interactions with MITF. PLoS Genet 10, e1004360, (2014)

17           Dvashi, Z., Shalom, H. J., Shohat, M., Ben-Meir, D., Ferber, S., Satchi-Fainaro, R. et al. Protein Phosphatase Magnesium Dependent 1A Governs the Wound Healing-Inflammation-Angiogenesis Cross Talk on Injury. Am J Pathol, (2014)

18           David, A., Liu, F., Tibelius, A., Vulprecht, J., Wald, D., Rothermel, U. et al. Lack of centrioles and primary cilia in STIL(-/-) mouse embryos. Cell Cycle 13, 2859-2868, (2014)

19           Cvekl, A. & Ashery-Padan, R. The cellular and molecular mechanisms of vertebrate lens development. Development 141, 4432-4447, (2014)

20           Benavente, C. A., Finkelstein, D., Johnson, D. A., Marine, J. C., Ashery-Padan, R. & Dyer, M. A. Chromatin remodelers HELLS and UHRF1 mediate the epigenetic deregulation of genes that drive retinoblastoma tumor progression. Oncotarget, (2014)

21           Zembrzycki, A., Chou, S. J., Ashery-Padan, R., Stoykova, A. & O'Leary, D. D. Sensory cortex limits cortical maps and drives top-down plasticity in thalamocortical circuits. Nat Neurosci 16, 1060-1067, (2013)

22           Wolf, L., Harrison, W., Huang, J., Xie, Q., Xiao, N., Sun, J. et al. Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300. Nucleic Acids Res, (2013)

23           Wolf, L., Gao, C. S., Gueta, K., Xie, Q., Chevallier, T., Podduturi, N. R. et al. Identification and Characterization of FGF2-Dependent mRNA:microRNA Networks During Lens Fiber Cell Differentiation. G3 (Bethesda), (2013)

24           Shaham, O., Gueta, K., Mor, E., Oren-Giladi, P., Grinberg, D., Xie, Q. et al. Pax6 Regulates Gene Expression in the Vertebrate Lens through miR-204. PLoS Genet 9, e1003357, (2013)

25           Farhy, C., Elgart, M., Shapira, Z., Oron-Karni, V., Yaron, O., Menuchin, Y. et al. Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells. PLoS One 8, e76489, (2013)

26           Bochner, R., Ziv, Y., Zeevi, D., Donyo, M., Abraham, L., Ashery-Padan, R. et al. Phosphatidylserine increases IKBKAP levels in a humanized knock-in IKBKAP mouse model. Hum Mol Genet, (2013)

27           Shaham, O., Menuchin, Y., Farhy, C. & Ashery-Padan, R. Pax6: a multi-level regulator of ocular development. Prog Retin Eye Res 31, 351-376, (2012).

28           Magenheim, J., Klein, A. M., Stanger, B. Z., Ashery-Padan, R., Sosa-Pineda, B., Gu, G. et al. Ngn3(+) endocrine progenitor cells control the fate and morphogenesis of pancreatic ductal epithelium. Dev Biol 359, 26-36, (2011)

29           Huang, J., Rajagopal, R., Liu, Y., Dattilo, L. K., Shaham, O., Ashery-Padan, R. et al. The mechanism of lens placode formation: a case of matrix-mediated morphogenesis. Dev Biol 355, 32-42, (2011)

30           Davis, N., Mor, E. & Ashery-Padan, R. Roles for Dicer1 in the patterning and differentiation of the optic cup neuroepithelium. Development 138, 127-138, (2011)

31           Kroeber, M., Davis, N., Holzmann, S., Kritzenberger, M., Shelah-Goraly, M., Ofri, R. et al. Reduced expression of Pax6 in lens and cornea of mutant mice leads to failure of chamber angle development and juvenile glaucoma. Hum Mol Genet, (2010)

32           He, S., Pirity, M. K., Wang, W. L., Wolf, L., Chauhan, B. K., Cveklova, K. et al. Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation. Epigenetics Chromatin 3, 21, (2010)

33           Bandah-Rozenfeld, D., Mizrahi-Meissonnier, L., Farhy, C., Obolensky, A., Chowers, I., Pe'er, J. et al. Homozygosity mapping reveals null mutations in FAM161A as a cause of autosomal-recessive retinitis pigmentosa. Am J Hum Genet 87, 382-391, (2010)

34           Tuoc, T. C., Radyushkin, K., Tonchev, A. B., Pinon, M. C., Ashery-Padan, R., Molnar, Z. et al. Selective cortical layering abnormalities and behavioral deficits in cortex-specific Pax6 knock-out mice. J Neurosci 29, 8335-8349, (2009)

35           Smith, A. N., Miller, L. A., Radice, G., Ashery-Padan, R. & Lang, R. A. Stage-dependent modes of Pax6-Sox2 epistasis regulate lens development and eye morphogenesis. Development 136, 2977-2985, (2009)

36           Shaham, O., Smith, A. N., Robinson, M. L., Taketo, M. M., Lang, R. A. & Ashery-Padan, R. Pax6 is essential for lens fiber cell differentiation. Development 136, 2567-2578, (2009)

37           Davis, N., Yoffe, C., Raviv, S., Antes, R., Berger, J., Holzmann, S. et al. Pax6 dosage requirements in iris and ciliary body differentiation. Dev Biol 333, 132-142, (2009)

38           Boretius, S., Michaelis, T., Tammer, R., Ashery-Padan, R., Frahm, J. & Stoykova, A. In vivo MRI of altered brain anatomy and fiber connectivity in adult pax6 deficient mice. Cereb Cortex 19, 2838-2847, (2009)

39           Baranes, K., Raz-Prag, D., Nitzan, A., Galron, R., Ashery-Padan, R., Rotenstreich, Y. et al. Conditional inactivation of the NBS1 gene in the mouse central nervous system leads to neurodegeneration and disorganization of the visual system. Exp Neurol 218, 24-32, (2009)

40           Pontoriero, G. F., Deschamps, P., Ashery-Padan, R., Wong, R., Yang, Y., Zavadil, J. et al. Cell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotype. Dev Dyn 237, 602-617, (2008)

41           Pinon, M. C., Tuoc, T. C., Ashery-Padan, R., Molnar, Z. & Stoykova, A. Altered molecular regionalization and normal thalamocortical connections in cortex-specific Pax6 knock-out mice. J Neurosci 28, 8724-8734, (2008)

42           Oron-Karni, V., Farhy, C., Elgart, M., Marquardt, T., Remizova, L., Yaron, O. et al. Dual requirement for Pax6 in retinal progenitor cells. Development 135, 4037-4047, (2008)

43           Davis-Silberman, N. & Ashery-Padan, R. Iris development in vertebrates; genetic and molecular considerations. Brain Res 1192, 17-28, (2008)

44           Brill, M. S., Snapyan, M., Wohlfrom, H., Ninkovic, J., Jawerka, M., Mastick, G. S. et al. A dlx2- and pax6-dependent transcriptional code for periglomerular neuron specification in the adult olfactory bulb. J Neurosci 28, 6439-6452, (2008)

45           Xu, S., Sunderland, M. E., Coles, B. L., Kam, A., Holowacz, T., Ashery-Padan, R. et al. The proliferation and expansion of retinal stem cells require functional Pax6. Dev Biol 304, 713-721, (2007)

46           Swamynathan, S. K., Katz, J. P., Kaestner, K. H., Ashery-Padan, R., Crawford, M. A. & Piatigorsky, J. Conditional deletion of the mouse Klf4 gene results in corneal epithelial fragility, stromal edema, and loss of conjunctival goblet cells. Mol Cell Biol 27, 182-194, (2007)

47           Strom, A., Bonal, C., Ashery-Padan, R., Hashimoto, N., Campos, M. L., Trumpp, A. et al. Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas. Development 134, 2719-2725, (2007)

48           Finkler, A., Ashery-Padan, R. & Fromm, H. CAMTAs: Calmodulin-binding transcription activators from plants to human. FEBS Lett 581, 3893-3898, (2007)

49           Bumsted-O'Brien, K. M., Hendrickson, A., Haverkamp, S., Ashery-Padan, R. & Schulte, D. Expression of the homeodomain transcription factor Meis2 in the embryonic and postnatal retina. J Comp Neurol 505, 58-72, (2007)

50           Alberstein, M., Amit, M., Vaknin, K., O'Donnell, A., Farhy, C., Lerenthal, Y. et al. Regulation of transcription of the RNA splicing factor hSlu7 by Elk-1 and Sp1 affects alternative splicing. Rna, (2007)

51           Yaron, O., Farhy, C., Marquardt, T., Applebury, M. & Ashery-Padan, R. Notch1 functions to suppress cone-photoreceptor fate specification in the developing mouse retina. Development 133, 1367-1378, (2006)

52           Hack, M. A., Saghatelyan, A., de Chevigny, A., Pfeifer, A., Ashery-Padan, R., Lledo, P. M. et al. Neuronal fate determinants of adult olfactory bulb neurogenesis. Nat Neurosci 8, 865-872, (2005)

53           Garcia, C. M., Yu, K., Zhao, H., Ashery-Padan, R., Ornitz, D. M., Robinson, M. L. et al. Signaling through FGF receptor-2 is required for lens cell survival and for withdrawal from the cell cycle during lens fiber cell differentiation. Dev Dyn 233, 516-527, (2005)

54           Dwivedi, D. J., Pontoriero, G. F., Ashery-Padan, R., Sullivan, S., Williams, T. & West-Mays, J. A. Targeted Deletion of AP-2{alpha} Leads to Disruption in Corneal Epithelial Cell Integrity and Defects in the Corneal Stroma. Invest Ophthalmol Vis Sci 46, 3623-3630, (2005)

55           Davis-Silberman, N., Kalich, T., Oron-Karni, V., Marquardt, T., Kroeber, M., Tamm, E. R. et al. Genetic dissection of Pax6 dosage requirements in the developing mouse eye. Hum Mol Genet 14, 2265-2276, (2005)

56           Beebe, D., Garcia, C., Wang, X., Rajagopal, R., Feldmeier, M., Kim, J. Y. et al. Contributions by members of the TGFbeta superfamily to lens development. Int J Dev Biol 48, 845-856, (2004)

57           Ashery-Padan, R., Zhou, X., Marquardt, T., Herrera, P., Toube, L., Berry, A. et al. Conditional inactivation of Pax6 in the pancreas causes early onset of diabetes. Dev Biol 269, 479-488, (2004)

58           Ahituv, N., Erven, A., Fuchs, H., Guy, K., Ashery-Padan, R., Williams, T. et al. An ENU-induced mutation in AP-2alpha leads to middle ear and ocular defects in Doarad mice. Mamm Genome 15, 424-432, (2004)

59           Baumer, N., Marquardt, T., Stoykova, A., Spieler, D., Treichel, D., Ashery-Padan, R. et al. Retinal pigmented epithelium determination requires the redundant activities of Pax2 and Pax6. Development 130, 2903-2915, (2003)

60           Baumer, N., Marquardt, T., Stoykova, A., Ashery-Padan, R., Chowdhury, K. & Gruss, P. Pax6 is required for establishing naso-temporal and dorsal characteristics of the optic vesicle. Development 129, 4535-4545, (2002)

61           Ashery-Padan, R. Somatic gene targeting in the developing and adult mouse retina. Methods 28, 457-464, (2002)

62           Schaft, J., Ashery-Padan, R., van der Hoeven, F., Gruss, P. & Stewart, A. F. Efficient FLP recombination in mouse ES cells and oocytes. Genesis 31, 6-10, (2001)

63           Marquardt, T., Ashery-Padan, R., Andrejewski, N., Scardigli, R., Guillemot, F. & Gruss, P. Pax6 is required for the multipotent state of retinal progenitor cells. Cell 105, 43-55, (2001)

64           Ashery-Padan, R. & Gruss, P. Pax6 lights-up the way for eye development. Curr Opin Cell Biol 13, 706-714, (2001)

65           Ashery-Padan, R., Marquardt, T., Zhou, X. & Gruss, P. Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye. Genes Dev 14, 2701-2711, (2000)

66           Ashery-Padan, R., Alvarez-Bolado, G., Klamt, B., Gessler, M. & Gruss, P. Fjx1, the murine homologue of the Drosophila four-jointed gene, codes for a putative secreted protein expressed in restricted domains of the developing and adult brain. Mech Dev 80, 213-217, (1999)

67           Goldberg, M., Lu, H., Stuurman, N., Ashery-Padan, R., Weiss, A. M., Yu, J. et al. Interactions among Drosophila nuclear envelope proteins lamin, otefin, and YA. Mol Cell Biol 18, 4315-4323, (1998)

68           Ashery-Padan, R., Weiss, A. M., Feinstein, N. & Gruenbaum, Y. Distinct regions specify the targeting of otefin to the nucleoplasmic side of the nuclear envelope. J Biol Chem 272, 2493-2499, (1997)

69           Ashery-Padan, R., Ulitzur, N., Arbel, A., Goldberg, M., Weiss, A. M., Maus, N. et al. Localization and posttranslational modifications of otefin, a protein required for vesicle attachment to chromatin, during Drosophila melanogaster development. Mol Cell Biol 17, 4114-4123, (1997)

70           Padan, R., Nainudel-Epszteyn, S., Goitein, R., Fainsod, A. & Gruenbaum, Y. Isolation and characterization of the Drosophila nuclear envelope otefin cDNA. J Biol Chem 265, 7808-7813, (1990)

71           Neville, L. F., Gnatt, A., Padan, R., Seidman, S. & Soreq, H. Anionic site interactions in human butyrylcholinesterase disrupted by two single point mutations. J Biol Chem 265, 20735-20738, (1990)